How It Works
Intestinal microbes. Artwork of the human intestinal lumen showing the microbial flora (coloured) present on the lining (pink). These microbes (such as bacteria) are beneficial and aid the digestion of food. Without them, many nutrients would be indigestible.

The good, the bad, and the ugly bacteria

Intestinal microbes. Artwork of the human intestinal lumen showing the microbial flora (coloured) present on the lining (pink). These microbes (such as bacteria) are beneficial and aid the digestion of food. Without them, many nutrients would be indigestible.

Your body is home to trillions of microbes, and you wouldn’t survive without them.

It might surprise you to know that only around half the cells that make up your body are actually human. The average person has an estimated one-to-one ratio of human cells to microbes, the majority of which are bacteria. Known as the microbiome, your body’s bacterial ecosystem has a huge influence on your health. Bacteria often get a bad rap. Some of them cause infections, make you feel sick, and a few even appear to feast on your flesh. That said, these harmful germs are in the minority. Fewer than five per cent of microbes are known to cause disease in humans and the majority of bacteria that call your body home are harmless.

 

Did you know: Approximately 1-3% of your body mass is bacteria – for an average person that’s between 0.8kg and 2.4kg!

 

Many species, particularly those that reside in our digestive systems, are highly beneficial. Researchers are only just starting to discover the extent to which gut bacteria influence our health. The bacteria that colonise your intestines (known as gut flora) help break down some of the foods that you can’t digest into nutrients that you can. They also produce some vitamins that your body can’t synthesise on its own, including K2 (which helps blood clot properly) and B12 (involved in several key functions, including protein metabolism). The overwhelming presence of good bacteria in a healthy gut helps suppress the growth and survival of bad bacteria, protecting us from illness.

 

Fermented foods such as kimchi and live yoghurt contain strains of good bacteria

 

Research suggests that the combination of different bacteria in your gut is an important factor in whether or not you become obese or develop diabetes. The composition of your microbiome can change how you store fat, how you regulate blood glucose levels and how your body responds to the hormones that regulate appetite. Obese individuals tend to have a less diverse microbiome, whereas the gut flora of lean people includes a wide variety of bacterial species.

 

Studies suggest that a diet full of junk food destroys around 30 percent of your beneficial gut bacteria

 

Although the majority of your body’s bacteria resides in your intestines, your skin also plays host to a multitude of microbes. Your skin flora helps regulate inflammation, a process that helps the body heal but can be damaging if left unchecked. Research by the University of Oregon found that we are each
surrounded by our own personal atmosphere of microbes. Your microbiome is unique like a fingerprint: it is even possible to identify someone from a sample of their bacterial ‘cloud’.

 

Click on the image for a closer look at bacterial anatomy

 

Diet is a very significant factor in the health of your gut flora. Both prebiotic and probiotic foods are beneficial to your microbiome, but what is the difference between the two?

Probiotic foods contain live bacteria that give your digestive system a helping hand. Foods that are made through fermentation – a process by which bacteria naturally present in the food start digesting its sugars – are rich in probiotics. This group includes yoghurt, sauerkraut, kimchi and some cheeses.

Prebiotic foods are also high in certain kinds of fibre, which we are unable to digest, but are a valuable source of nutrition for the bacteria in our guts. While all prebiotics are fibres, not all fibres are prebiotic; many vegetables, legumes, grains and nuts are naturally high in the types of fibre that keep gut bacteria healthy.

 

A selection of prebiotic foods healthy for the gut and immunity, including onions, leeks, nuts, seeds and pulses.

 

The bad and the ugly

Although only a small fraction of known bacterial species causes disease, they are capable of wreaking havoc on our bodies. Harmful bacteria can enter the body in several ways. For instance, we can inhale or ingest them, or they can enter through broken skin.

Once inside, they can reach their target site, such as the lungs or intestines, where they attach to our cells and multiply. Our bodies provide these bacteria with nutrients, but in return they release toxins, which can damage our tissues.

Our immune system provides some protection against these microscopic invaders. Immune cells can identify and destroy pathogens, but some bacteria have evolved methods of evading our internal defence mechanisms. It is in cases where these hardy germs persist that we need the help of antibiotics to eliminate infections before they spread.

Bacteria adapt to their environment so quickly that if any survive, they can develop immunity to these medications. The rise of antibiotic-resistant ‘superbugs’, which can cause life-threatening infections, is an increasingly serious threat to global health.

 

Click on the image for a larger view of some of the deadliest bacteria

 

Discover more amazing science in the latest issue of How It Works. It’s available from all good retailers, or you can order it online from the ImagineShop. If you have a tablet or smartphone, you can also download the digital version onto your iOS or Android device. To make sure you never miss an issue of How It Works, make sure you subscribe today!

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